Article Abstract

Caspofungin resistant disseminated candidiasis in a 7-year old girl with T cell lymphoma: a case report

Authors: Michael Schmalz, Manasa Joysula, Jack H. Staddon, Arthur Feinberg


Immunocompromised patients are at increased risk of disseminated candidiasis. Guidelines for the treatment of invasive candidiasis were last published in 2009, but resistance to the recommended treatment has recently been described in the literature. Here we present the case of an immunocompromised child with T-cell lymphoma who died secondary to disseminated candidiasis despite prolonged antifungal therapy. Awareness of the increasing resistance patterns of Candida when caring for immunocompromised patients, especially pediatric patients, may improve treatment and create better patient outcomes.