Yu-Jia Yang, MD, PhD

Xiangya Hospital of Central South University, China

Dr. Yu-Jia Yang serves as the Editor-in-chief of Translational Pediatrics (www.thetp.org) and Chinese Journal of Contemporary Pediatrics (www.cjcp.org), Consultant of Neonatal Group, Chinese Medical Association (CMA) Academy of Pediatrics, & Neonatal Professional Board of Chinese Medical Doctor Association (CMDA), & Academic Board of the Key Laboratory in Neonatal Disease, Children's Hospital of Fudan University, Shanghai, China. He is a supervisor for doctoral candidates and enjoys special allowance from State Council of China.

He graduated from Tongji University Medical College (formerly Shanghai Railway Medical College) in 1966, and then received his master degree and PhD degree in Central South University Xiangya Medical College (formerly Hunan Medical College) in 1981 and 1990, respectively.

In 1988, he was trained in Montreal Neurological Institute, McGill University under the supervision of Prof. Hanna M. Pappius. He was promoted to professor at Xiangya Hospital of Central South University in 1992. He served as the Chairmen of the Department of Pediatrics of Xiangya Hospital from 1994 to 2004. In 1996, he studied in the Division of Neurology, Lund University, Sweden, as a senior visiting scholar; in the same year, he conducted a short- term academic exchange in the Department of Neonatology at University of Maryland School of Medicine for one month. In 1999, Prof. Yang established Chinese Journal of Contemporary Pediatrics and has been served as its editor-in-chief till now. Yang served as the Deputy Director of Neonatal Group, Chinese Medical Association (CMA) Academy of Pediatrics from 2007 to 2010 and Director of academic committee of the Key Laboratory of Neonatal Disease of Ministry of Health at the Children's Hospital of Fudan University from 2009 to 2012.

His main research interests include the prevention and treatment of pediatric brain edema and neonatal brain injuries, especially the treatment of neonatal hypoxic-ischemic encephalopathy using hyperbaric oxygenation and stem cell transplantation. In late 1970s, under the supervision of Prof. Pei-Lan Yu, a famous expert in pediatric brain edema in China, he participated in the establishment of the animal models of infectious brain edema. In the following decades, he and his research teams conducted massive amounts of research on the pathogenesis of cerebral edema and the molecular mechanisms of traditional Chinese medicine in treating brain edema. Prof. Yang and his colleagues for the first time reported that hyperbaric oxygen can stimulate the proliferation of endogenous neural stem cells and promote them to differentiate into neurons in neonatal rats with hypoxic-ischemic brain damage (HIBD). They also demonstrated that, with totally different toxicities from high-concentration oxygen, hyperbaric oxygen will not cause retinopathy of prematurity or lung injuries. They also have explored the protective roles of intracranial transplantation of multiple stem cells on neonatal rats with HIBD. Recently they have completed a new study on the treatment of neonatal rats with HIBD using the transplantation of dental pulp stem cells. Prof. Yang has been responsible for or engaged in 18 State-level or province-level research projects on pediatric brain injuries, including 4 projects supported by National Natural Science Fund. He has won 12 State-level or province-level scientific awards, including a National Award for Science and Technology Advancement (2nd Class) in 1990. He has trained more than 20 doctoral candidates.

He has authored several books including Pediatric Cerebral Edema and Increased Intracranial Pressure, Pediatric Stubborn Diseases, National Medical Qualification Examination - Pediatrics, Selected Examination Questions for Pediatrics, Neonatal Hypoxic-ischemic Encephalopathy, and Neonatal Jaundice.

He is also the co-author of two textbooks of pediatrics (one for 8-year program medical students, organized by Ministry of Health, and the other organized by the Ministry of Education) and several other books including Practical Neonatology and Pediatric Emergency Medicine.

He has published more than 100 articles in domestic and international peer-reviewed journals.

Zhigang Cao, MD, PhD

AME Publishing Company, Hong Kong, China

Dr. Zhigang Cao is currently vice president of AME Publishing Company and Research Assistant for breast and liver cancer. Dr. Cao received his medical and research training in Shanghai Jiaotong University and Fudan University, where he was awarded multiple prizes and where he received Master and Ph.D. degree for research in Oncology. After that, Dr. Cao worked in the State Key Laboratory of Oncogenes & Related Genes of Shanghai Cancer Institute and Breast Cancer Institute in Fudan University Shanghai Cancer Center for about 10 years.

His research interests mainly focus on understanding the molecular mechanism of breast and liver cancer. Dr. Cao has been in charge of several research projects, including National Natural Science Foundation of China and so on. To date, his works have been published in Cancer Research, Oncotarget, Breast Cancer Research and Treatment, PLoS One, Journal of Thoracic Disease and other journals.