How to cite item

An evidence-based standardized protocol for anticoagulation following congenital heart surgery

  
@article{TP20638,
	author = {Catherine Deshaies and Nancy Poirier and Paul Khairy},
	title = {An evidence-based standardized protocol for anticoagulation following congenital heart surgery},
	journal = {Translational Pediatrics},
	volume = {7},
	number = {4},
	year = {2018},
	keywords = {},
	abstract = {Unfractionated heparin is the cornerstone of prevention and treatment of thrombosis in children undergoing cardiac surgery due to its short half-life and reversibility using protamine. Yet, optimal titration in children remains challenging (1). Age-related differences in heparin clearance (2), protein binding activity (3,4) and anti-thrombin concentration (5-8), which are most pronounced in neonates and young infants, obscure the applicability of standard adult dosing protocols.},
	issn = {2224-4344},	url = {http://tp.amegroups.com/article/view/20638}
}