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Consideration of Glucocorticoids and Escherichia coli-derived L-asparaginase in the treatment of pediatric acute lymphoblastic leukemia

   
@article{TP1848,
	author = {Hidehiko Narazaki and Takeshi Asano},
	title = {Consideration of Glucocorticoids and  Escherichia coli -derived L-asparaginase in the treatment of pediatric acute lymphoblastic leukemia},
	journal = {Translational Pediatrics},
	volume = {2},
	number = {2},
	year = {2013},
	keywords = {},
	abstract = {Glucocorticoids (GCs) are steroid hormones these are synthesized in the adrenal cortex. After binding to the nuclear glucocorticoid receptor (GR), activated GR complexes play a major role in immune system regulation by exerting a variety of effects such as inhibition of cyclooxygenase and inflammatory cytokines (IL-1, IL-2, IL-5, IL-6, INF-γ) synthesis, neutrophil induction, lymphocyte activation, etc. (1).},
	issn = {2224-4344},	url = {https://tp.amegroups.org/article/view/1848}
}