Leveraging big data to advance knowledge in pediatric heart failure and heart transplantation

Justin Godown, Michael Gaies, James D. Wilkinson


Despite many therapeutic advances for children with heart failure and those who undergo heart transplantation, robust evidence to guide clinical practice remains limited. The approach to these patients has been largely based upon available evidence in the adult population. Each pediatric heart center has a relatively small number of heart failure and heart transplant patients, making single-center studies largely underpowered.